Thursday, March 28, 2013

The inevitable part for us-oral health!

What a cool spring in 2013, the sunshine outside is comfortable for us to enjoy the whole day! I believe that most of us have a special feeling for this season! It made me think of the spring outing! It seems that I did not have such wonderful acativity after graduation! Those days were unforgettable! We are always busy working for our future, is it really the era of money talks?

Last week I paid a visit to my friend at hospital, she suffered the operation, I mean the oral health! You know, oral health now gets more and more important! If we don’t develop a good habbit into this, we will get the pain for a long time! Meanwhile, what I want to say is the opsigenes, somebody tell me that Paracetamol for pain relief after surgical removal of lower wisdom teeth!

Paracetamol has been commonly used for the relief of postoperative pain following oral surgery. In this review we investigated the optimal dose of paracetamol and the optimal time for drug administration to provide pain relief, taking into account the side effects of different doses of the drug. This will inform dentists and their patients of the best strategy for pain relief after the surgical removal of wisdom teeth. To assess the beneficial and harmful effects of paracetamol for pain relief after surgical removal of lower wisdom teeth, compared to placebo, at different doses and administered postoperatively.

The result like this: Twenty-one trials met the inclusion criteria. A total of 2048 patients were initially enrolled in the trials (1148 received paracetamol, and 892 the placebo) and of these 1968 (96%) were included in the meta-analysis (1133 received paracetamol, and 835 the placebo). Paracetamol provided a statistically significant benefit when compared with placebo for pain relief and pain intensity at both 4 and 6 hours. Most studies were found to have moderate risk of bias, with poorly reported allocation concealment being the main problem. Risk ratio values for pain relief at 4 hours 2.85 (95% confidence interval (CI) 1.89 to 4.29), and at 6 hours 3.32 (95% CI 1.88 to 5.87). A statistically significant benefit was also found between up to 1000 mg and 1000 mg doses, the higher the dose giving greater benefit for each measure at both time points. There was no statistically significant difference between the number of patients who reported adverse events, overall this being 19% in the paracetamol group and 16% in the placebo group.

Finally we got the conclusion: Paracetamol is a safe, effective drug for the treatment of postoperative pain following the surgical removal of lower wisdom teeth. From the introduction above, it’s persuasive for all of us that who care about the wisdom teeth! In my eyes, most of us would experience that one day! Then knowing more details about oral health is essential! It’s the inevitable part for us!